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Stimuli-responsive polypeptide nanogels for trypsin inhibition

A new type of hydrophilic, biocompatible, and biodegradable polypeptide nanogel depots loaded with the natural serine protease inhibitor α1-antitrypsin (AAT) was applied for the inhibition of the inflammatory mediator trypsin. Two types of nanogels were prepared from linear synthetic polypeptides ba...

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Detalles Bibliográficos
Autores principales: Šálek, Petr, Dvořáková, Jana, Hladysh, Sviatoslav, Oleshchuk, Diana, Pavlova, Ewa, Kučka, Jan, Proks, Vladimír
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235903/
https://www.ncbi.nlm.nih.gov/pubmed/35812252
http://dx.doi.org/10.3762/bjnano.13.45