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Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity

Distant organ metastasis is linked to poor prognosis during cancer progression. The expression level of the focal adhesion adapter protein paxillin varies among different human cancers, but its role in tumor progression is unclear. Herein we utilize a newly generated PyMT mammary tumor mouse model w...

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Detalles Bibliográficos
Autores principales: Xu, Weiyi, Alpha, Kyle M., Zehrbach, Nicholas M., Turner, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236150/
https://www.ncbi.nlm.nih.gov/pubmed/34851720
http://dx.doi.org/10.1091/mbc.E21-09-0432