Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design

Microtubules and their post-translational modifications are involved in major cellular processes. In severe diseases such as neurodegenerative disorders, tyrosinated tubulin and tyrosinated microtubules are in lower concentration. We present here a mechanistic mathematical model of the microtubule t...

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Detalles Bibliográficos
Autores principales: Grignard, Jeremy, Lamamy, Véronique, Vermersch, Eva, Delagrange, Philippe, Stephan, Jean-Philippe, Dorval, Thierry, Fages, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236252/
https://www.ncbi.nlm.nih.gov/pubmed/35759459
http://dx.doi.org/10.1371/journal.pcbi.1010236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236252/
https://www.ncbi.nlm.nih.gov/pubmed/35759459
http://dx.doi.org/10.1371/journal.pcbi.1010236

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