Reconstructing tumor clonal lineage trees incorporating single-nucleotide variants, copy number alterations and structural variations

MOTIVATION: Cancer develops through a process of clonal evolution in which an initially healthy cell gives rise to progeny gradually differentiating through the accumulation of genetic and epigenetic mutations. These mutations can take various forms, including single-nucleotide variants (SNVs), copy...

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Detalles Bibliográficos
Autores principales: Fu, Xuecong, Lei, Haoyun, Tao, Yifeng, Schwartz, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
ISCB/Ismb 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236577/
https://www.ncbi.nlm.nih.gov/pubmed/35758777
http://dx.doi.org/10.1093/bioinformatics/btac253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236577/
https://www.ncbi.nlm.nih.gov/pubmed/35758777
http://dx.doi.org/10.1093/bioinformatics/btac253

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