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Reconstructing tumor clonal lineage trees incorporating single-nucleotide variants, copy number alterations and structural variations
MOTIVATION: Cancer develops through a process of clonal evolution in which an initially healthy cell gives rise to progeny gradually differentiating through the accumulation of genetic and epigenetic mutations. These mutations can take various forms, including single-nucleotide variants (SNVs), copy...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236577/ https://www.ncbi.nlm.nih.gov/pubmed/35758777 http://dx.doi.org/10.1093/bioinformatics/btac253 |