Cytotoxic CD4(+) T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts

Increasing attention has been directed to cytotoxic CD4(+) T cells (CD4CTLs) in different pathologies, both in humans and mice. The impact of CD4CTLs in immunity and the mechanisms controlling their generation, however, remain poorly understood. Here, we show that CD4CTLs abundantly differentiate du...

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Detalles Bibliográficos
Autores principales: Barbosa, Carlos-Henrique D, Canto, Fábio B, Gomes, Ariel, Brandao, Layza M, Lima, Jéssica R, Melo, Guilherme A, Granato, Alessandra, Neves, Eula GA, Dutra, Walderez O, Oliveira, Ana-Carolina, Nóbrega, Alberto, Bellio, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236613/
https://www.ncbi.nlm.nih.gov/pubmed/35670567
http://dx.doi.org/10.7554/eLife.74636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236613/
https://www.ncbi.nlm.nih.gov/pubmed/35670567
http://dx.doi.org/10.7554/eLife.74636

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