Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin

Research and therapeutic applications using human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) require robust differentiation strategies. Efforts to improve hPSC-CM differentiation have largely overlooked the role of extracellular matrix (ECM). The present study investigates the ability o...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jianhua, Gregorich, Zachery R, Tao, Ran, Kim, Gina C, Lalit, Pratik A, Carvalho, Juliana L, Markandeya, Yogananda, Mosher, Deane F, Palecek, Sean P, Kamp, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236614/
https://www.ncbi.nlm.nih.gov/pubmed/35758861
http://dx.doi.org/10.7554/eLife.69028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236614/
https://www.ncbi.nlm.nih.gov/pubmed/35758861
http://dx.doi.org/10.7554/eLife.69028

Ejemplares similares