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“But Mouse, You Are Not Alone”: On Some Severe Acute Respiratory Syndrome Coronavirus 2 Variants Infecting Mice

In silico predictions combined with in vitro, in vivo, and in situ observations collectively suggest that mouse adaptation of the severe acute respiratory syndrome 2 virus requires an aromatic substitution in position 501 or position 498 (but not both) of the spike protein’s receptor binding domain....

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Detalles Bibliográficos
Autores principales: Kuiper, Michael J, Wilson, Laurence O W, Mangalaganesh, Shruthi, Lee, Carol, Reti, Daniel, Vasan, Seshadri S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236659/
https://www.ncbi.nlm.nih.gov/pubmed/35022734
http://dx.doi.org/10.1093/ilar/ilab031