Perisciatic Nerve Dexmedetomidine Alleviates Spinal Oxidative Stress and Improves Peripheral Mitochondrial Dynamic Equilibrium in a Neuropathic Pain Mouse Model in an AMPK-Dependent Manner

Neuropathic pain (NPP) is a debilitating clinical condition that presently has few effective treatments. NPP is caused by uncontrolled central oxidative stress and inflammation. Preliminary studies indicate that dexmedetomidine (DEX), an agonist of the alpha-2 adrenergic receptor, is beneficial for...

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Detalles Bibliográficos
Autores principales: Mu, Yang, Mei, Yang, Chen, Yaohua, Li, Yuping, Zhu, Dan, Cui, Jian, Yu, Lehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236761/
https://www.ncbi.nlm.nih.gov/pubmed/35769812
http://dx.doi.org/10.1155/2022/6889676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236761/
https://www.ncbi.nlm.nih.gov/pubmed/35769812
http://dx.doi.org/10.1155/2022/6889676

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