Acute lymphoblastic leukemia displays a distinct highly methylated genome

DNA methylation is tightly regulated during development and is stably maintained in healthy cells. In contrast, cancer cells are commonly characterized by a global loss of DNA methylation co-occurring with CpG island hypermethylation. In acute lymphoblastic leukemia (ALL), the commonest childhood ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Hetzel, Sara, Mattei, Alexandra L., Kretzmer, Helene, Qu, Chunxu, Chen, Xiang, Fan, Yiping, Wu, Gang, Roberts, Kathryn G., Luger, Selina, Litzow, Mark, Rowe, Jacob, Paietta, Elisabeth, Stock, Wendy, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Mullighan, Charles G., Meissner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236905/
https://www.ncbi.nlm.nih.gov/pubmed/35590059
http://dx.doi.org/10.1038/s43018-022-00370-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236905/
https://www.ncbi.nlm.nih.gov/pubmed/35590059
http://dx.doi.org/10.1038/s43018-022-00370-5

Ejemplares similares