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Poor outcome of pediatric patients with acute myeloid leukemia harboring high FLT3/ITD allelic ratios

Activating FLT3 mutations are the most common mutations in acute myeloid leukemia (AML), but the optimal threshold of FLT3/ITD allelic ratio (AR) among pediatric AML patients remains controversial. Here, we present the outcome and prognostic significance of FLT3/ITD AR analysis among pediatric patie...

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Detalles Bibliográficos
Autores principales: Qiu, Kun-yin, Liao, Xiong-yu, Liu, Yong, Huang, Ke, Li, Yang, Fang, Jian-pei, Zhou, Dun-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237020/
https://www.ncbi.nlm.nih.gov/pubmed/35760968
http://dx.doi.org/10.1038/s41467-022-31489-9