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HS3ST2 expression induces the cell autonomous aggregation of tau

Heparan sulfates have long been known to intracellularly accumulate in Alzheimer’s disease neurons, where they colocalize with neurofibrillary tangles made of abnormally phosphorylated and aggregated tau protein. However, the reasons and consequences of the heparan sulfates accumulation in the Alzhe...

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Detalles Bibliográficos
Autores principales: Huynh, M. B., Rebergue, N., Merrick, H., Gomez-Henao, W., Jospin, E., Biard, D. S. F., Papy-Garcia, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237029/
https://www.ncbi.nlm.nih.gov/pubmed/35760982
http://dx.doi.org/10.1038/s41598-022-13486-6