Mice with Trp53 and Rb1 deficiency in chondrocytes spontaneously develop chondrosarcoma via overactivation of YAP signaling

Chondrosarcoma (CHS) is a rare type of soft sarcoma with increased production of cartilage matrix arising from soft bone tissues. Currently, surgical resection is the primary clinical treatment for chondrosarcoma due to the poor response to radiotherapy and chemotherapy. However, the therapeutic eff...

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Detalles Bibliográficos
Autores principales: Li, Yang, Yang, Shuting, Liu, Yang, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237030/
https://www.ncbi.nlm.nih.gov/pubmed/35760773
http://dx.doi.org/10.1038/s41419-022-04916-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237030/
https://www.ncbi.nlm.nih.gov/pubmed/35760773
http://dx.doi.org/10.1038/s41419-022-04916-4

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