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G1/S restriction point coordinates phasic gene expression and cell differentiation

Pluripotent embryonic stem cells have a unique cell cycle structure with a suppressed G1/S restriction point and little differential expression across the cell cycle phases. Here, we evaluate the link between G1/S restriction point activation, phasic gene expression, and cellular differentiation. Ex...

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Detalles Bibliográficos
Autores principales: DeVeale, Brian, Liu, Leqian, Boileau, Ryan, Swindlehurst-Chan, Jennifer, Marsh, Bryan, Freimer, Jacob W., Abate, Adam, Blelloch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237072/
https://www.ncbi.nlm.nih.gov/pubmed/35760790
http://dx.doi.org/10.1038/s41467-022-31101-0