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G1/S restriction point coordinates phasic gene expression and cell differentiation
Pluripotent embryonic stem cells have a unique cell cycle structure with a suppressed G1/S restriction point and little differential expression across the cell cycle phases. Here, we evaluate the link between G1/S restriction point activation, phasic gene expression, and cellular differentiation. Ex...
Autores principales: | DeVeale, Brian, Liu, Leqian, Boileau, Ryan, Swindlehurst-Chan, Jennifer, Marsh, Bryan, Freimer, Jacob W., Abate, Adam, Blelloch, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237072/ https://www.ncbi.nlm.nih.gov/pubmed/35760790 http://dx.doi.org/10.1038/s41467-022-31101-0 |
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