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IDO1 plays a tumor-promoting role via MDM2-mediated suppression of the p53 pathway in diffuse large B-cell lymphoma

With the intensive therapeutic strategies, diffuse large B-cell lymphoma (DLBCL) is still a fatal disease due to its progressive characteristics. Indoleamine 2,3-dioxygenase 1 (IDO1) is a key regulator that catalyzes the commitment step of the kynurenine pathway in the immune system, its aberrant ac...

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Detalles Bibliográficos
Autores principales: Sun, Chengtao, Li, Mengzhen, Zhang, Lian, Sun, Feifei, Chen, Huimou, Xu, Yanjie, Lan, Yingxia, Zhang, Li, Lu, Suying, Zhu, Jia, Huang, Junting, Wang, Juan, Hu, Yang, Feng, Yanfen, Zhang, Yizhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237101/
https://www.ncbi.nlm.nih.gov/pubmed/35760783
http://dx.doi.org/10.1038/s41419-022-05021-2