Estimation of Free Phenytoin Concentration in Critically Ill Patients with Hypoalbuminemia: Direct-measurement vs Traditional Equations

BACKGROUND: In critically ill patients with low albumin, dose individualization of phenytoin is a challenge. The currently used Sheiner–Tozer equation does not accurately predict the free phenytoin concentration in serum and can result in incorrect dose modifications. The best measure to advocate in...

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Detalles Bibliográficos
Autores principales: Wilfred, Premila M, Mathew, Sumith, Chacko, Binila, Prabha, Ratna, Mathew, Binu Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237157/
https://www.ncbi.nlm.nih.gov/pubmed/35836626
http://dx.doi.org/10.5005/jp-journals-10071-24235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237157/
https://www.ncbi.nlm.nih.gov/pubmed/35836626
http://dx.doi.org/10.5005/jp-journals-10071-24235

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