The Anti-Glioma Effect of Juglone Derivatives through ROS Generation

Juglone has been extensively reported as a natural antitumor pigment. However, it is easy to be oxidized due to active hydroxy in the quinone. Here, we designed some new juglone derivatives, as the hydroxy was replaced by methyl (D1), allyl (D2), butyl (D3), and benzyl (D4) groups. Nuclear magnetic...

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Detalles Bibliográficos
Autores principales: Zhang, Jinsen, Fu, Minjie, Wu, Jinfeng, Fan, Fengfeng, Zhang, Xin, Li, Chunjie, Yang, Hui, Wu, Yonghe, Yin, Yiming, Hua, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237211/
https://www.ncbi.nlm.nih.gov/pubmed/35774612
http://dx.doi.org/10.3389/fphar.2022.911760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237211/
https://www.ncbi.nlm.nih.gov/pubmed/35774612
http://dx.doi.org/10.3389/fphar.2022.911760

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