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CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells

The development of CRISPR-based gene-editing technologies has brought an unprecedented revolution in the field of genome engineering. Cas12a, a member of the Class 2 Type V CRISPR-associated endonuclease family distinct from Cas9, has been repurposed and developed into versatile gene-editing tools w...

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Detalles Bibliográficos
Autores principales: Wang, Chengkun, Xia, Qiong, Zhang, Qianhe, Qu, Yuanhao, Su, Stephen, Cheng, Jason K. W., Hughes, Nicholas W., Cong, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237396/
https://www.ncbi.nlm.nih.gov/pubmed/35774104
http://dx.doi.org/10.3389/fcell.2021.719705