Copper Acts Synergistically With Fluconazole in Candida glabrata by Compromising Drug Efflux, Sterol Metabolism, and Zinc Homeostasis

The synergistic combinations of drugs are promising strategies to boost the effectiveness of current antifungals and thus prevent the emergence of resistance. In this work, we show that copper and the antifungal fluconazole act synergistically against Candida glabrata, an opportunistic pathogenic ye...

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Detalles Bibliográficos
Autores principales: Gaspar-Cordeiro, Ana, Amaral, Catarina, Pobre, Vânia, Antunes, Wilson, Petronilho, Ana, Paixão, Paulo, Matos, António P., Pimentel, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237516/
https://www.ncbi.nlm.nih.gov/pubmed/35774458
http://dx.doi.org/10.3389/fmicb.2022.920574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237516/
https://www.ncbi.nlm.nih.gov/pubmed/35774458
http://dx.doi.org/10.3389/fmicb.2022.920574

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