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Copper Acts Synergistically With Fluconazole in Candida glabrata by Compromising Drug Efflux, Sterol Metabolism, and Zinc Homeostasis
The synergistic combinations of drugs are promising strategies to boost the effectiveness of current antifungals and thus prevent the emergence of resistance. In this work, we show that copper and the antifungal fluconazole act synergistically against Candida glabrata, an opportunistic pathogenic ye...
Autores principales: | Gaspar-Cordeiro, Ana, Amaral, Catarina, Pobre, Vânia, Antunes, Wilson, Petronilho, Ana, Paixão, Paulo, Matos, António P., Pimentel, Catarina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237516/ https://www.ncbi.nlm.nih.gov/pubmed/35774458 http://dx.doi.org/10.3389/fmicb.2022.920574 |
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