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UPLC-MS/MS Technology for the Quantitative Methodology and Pharmacokinetic Analysis of Voxtalisib in Rat Plasma

Voxtalisib, is a specific, effective, and reversible dual inhibitor, which inhibits both pan-class I phosphoinositide 3-kinase (PI3K) and mechanistic target of rapamycin (mTOR). To date, voxtalisib has been studied in trials for melanoma, lymphoma, glioblastoma, breast cancer, and other cancers. In...

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Detalles Bibliográficos
Autores principales: Li, Qingqing, Liu, Ya-nan, Wang, Jing, Hu, Yingying, Hu, Jinyu, Xu, Ren-ai, Shao, Liu, Chen, Lianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237521/
https://www.ncbi.nlm.nih.gov/pubmed/35774599
http://dx.doi.org/10.3389/fphar.2022.914733