Solution Structure of Tubuliform Spidroin N-Terminal Domain and Implications for pH Dependent Dimerization

The spidroin N-terminal domain (NT) is responsible for high solubility and pH-dependent assembly of spider silk proteins during storage and fiber formation, respectively. It forms a monomeric five-helix bundle at neutral pH and dimerizes at lowered pH, thereby firmly interconnecting the spidroins. M...

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Detalles Bibliográficos
Autores principales: Šede, Megija, Fridmanis, Jēkabs, Otikovs, Martins, Johansson, Jan, Rising, Anna, Kronqvist, Nina, Jaudzems, Kristaps
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237525/
https://www.ncbi.nlm.nih.gov/pubmed/35775078
http://dx.doi.org/10.3389/fmolb.2022.936887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237525/
https://www.ncbi.nlm.nih.gov/pubmed/35775078
http://dx.doi.org/10.3389/fmolb.2022.936887

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