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Crystallographic study, biological assessment and POM/Docking studies of pyrazoles-sulfonamide hybrids (PSH): Identification of a combined Antibacterial/Antiviral pharmacophore sites leading to in-silico screening the anti-Covid-19 activity

The discovery and development of new potent antimicrobial and antioxidant agents is an essential lever to protect living beings against pathogenic microorganisms and free radicals. In this regard, new functionalized pyrazoles have been synthesized using a simple and accessible approach. The synthesi...

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Detalles Bibliográficos
Autores principales: Chalkha, Mohammed, Nakkabi, Asmae, Hadda, Taibi Ben, Berredjem, Malika, Moussaoui, Abdelfattah El, Bakhouch, Mohamed, Saadi, Mohamed, Ammari, Lahcen El, Almalki, Faisal A., Laaroussi, Hamid, Jevtovic, Violeta, Yazidi, Mohamed El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237569/
https://www.ncbi.nlm.nih.gov/pubmed/35782312
http://dx.doi.org/10.1016/j.molstruc.2022.133605