Examining clustered somatic mutations with SigProfilerClusters

MOTIVATION: Clustered mutations are found in the human germline as well as in the genomes of cancer and normal somatic cells. Clustered events can be imprinted by a multitude of mutational processes, and they have been implicated in both cancer evolution and development disorders. Existing tools for...

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Detalles Bibliográficos
Autores principales: Bergstrom, Erik N, Kundu, Mousumy, Tbeileh, Noura, Alexandrov, Ludmil B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237733/
https://www.ncbi.nlm.nih.gov/pubmed/35595234
http://dx.doi.org/10.1093/bioinformatics/btac335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237733/
https://www.ncbi.nlm.nih.gov/pubmed/35595234
http://dx.doi.org/10.1093/bioinformatics/btac335

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