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The role of BAG3 in dilated cardiomyopathy and its association with Charcot-Marie-Tooth disease type 2
Bcl2-associated athanogene 3 (BAG3) is a multifunctional cochaperone responsible for protein quality control within cells. BAG3 interacts with chaperones HSPB8 and Hsp70 to transport misfolded proteins to the Microtubule Organizing Center (MTOC) and degrade them in autophagosomes in a process known...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pacini Editore Srl
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237749/ https://www.ncbi.nlm.nih.gov/pubmed/35832504 http://dx.doi.org/10.36185/2532-1900-071 |