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Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology

Tau is a predominantly neuronal, soluble and natively unfolded protein that can bind and stabilize microtubules in the central nervous system. Tau has been extensively studied over several decades, especially in the context of neurodegenerative diseases where it can aberrantly aggregate to form a sp...

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Detalles Bibliográficos
Autores principales: Paterno, Giavanna, Bell, Brach M., Gorion, Kimberly-Marie M., Prokop, Stefan, Giasson, Benoit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237980/
https://www.ncbi.nlm.nih.gov/pubmed/35765058
http://dx.doi.org/10.1186/s40478-022-01394-9