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Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology
Tau is a predominantly neuronal, soluble and natively unfolded protein that can bind and stabilize microtubules in the central nervous system. Tau has been extensively studied over several decades, especially in the context of neurodegenerative diseases where it can aberrantly aggregate to form a sp...
Autores principales: | Paterno, Giavanna, Bell, Brach M., Gorion, Kimberly-Marie M., Prokop, Stefan, Giasson, Benoit I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237980/ https://www.ncbi.nlm.nih.gov/pubmed/35765058 http://dx.doi.org/10.1186/s40478-022-01394-9 |
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