Manipulating base quality scores enables variant calling from bisulfite sequencing alignments using conventional bayesian approaches

BACKGROUND: Calling germline SNP variants from bisulfite-converted sequencing data poses a challenge for conventional software, which have no inherent capability to dissociate true polymorphisms from artificial mutations induced by the chemical treatment. Nevertheless, SNP data is desirable both for...

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Detalles Bibliográficos
Autores principales: Nunn, Adam, Otto, Christian, Fasold, Mario, Stadler, Peter F, Langenberger, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237988/
https://www.ncbi.nlm.nih.gov/pubmed/35764934
http://dx.doi.org/10.1186/s12864-022-08691-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237988/
https://www.ncbi.nlm.nih.gov/pubmed/35764934
http://dx.doi.org/10.1186/s12864-022-08691-6

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