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Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies

Regulatory agencies rely upon rodent in vivo acute oral toxicity data to determine hazard categorization, require appropriate precautionary labeling, and perform quantitative risk assessments. As the field of toxicology moves toward animal-free new approach methodologies (NAMs), there is a pressing...

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Detalles Bibliográficos
Autores principales: Karmaus, Agnes L, Mansouri, Kamel, To, Kimberly T, Blake, Bevin, Fitzpatrick, Jeremy, Strickland, Judy, Patlewicz, Grace, Allen, David, Casey, Warren, Kleinstreuer, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237992/
https://www.ncbi.nlm.nih.gov/pubmed/35426934
http://dx.doi.org/10.1093/toxsci/kfac042