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Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies
Regulatory agencies rely upon rodent in vivo acute oral toxicity data to determine hazard categorization, require appropriate precautionary labeling, and perform quantitative risk assessments. As the field of toxicology moves toward animal-free new approach methodologies (NAMs), there is a pressing...
Autores principales: | Karmaus, Agnes L, Mansouri, Kamel, To, Kimberly T, Blake, Bevin, Fitzpatrick, Jeremy, Strickland, Judy, Patlewicz, Grace, Allen, David, Casey, Warren, Kleinstreuer, Nicole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237992/ https://www.ncbi.nlm.nih.gov/pubmed/35426934 http://dx.doi.org/10.1093/toxsci/kfac042 |
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