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PITX2C increases the stemness features of hepatocellular carcinoma cells by up-regulating key developmental factors in liver progenitor

BACKGROUND: Tumor cells exhibited phenotypic and molecular characteristics similar to their lineage progenitor cells. Liver developmental signaling pathways are showed to be associated with HCC development and oncogenesis. The similarities of expression profiling between liver progenitors (LPs) and...

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Detalles Bibliográficos
Autores principales: Jiang, Lingxi, Wang, Xia, Ma, Fangfang, Wang, Xuelong, Shi, Minmin, Yan, Qian, Liu, Ming, Chen, Juan, Shi, Chaoran, Guan, Xin-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238105/
https://www.ncbi.nlm.nih.gov/pubmed/35765089
http://dx.doi.org/10.1186/s13046-022-02424-z