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Probucol promotes osteoblasts differentiation and prevents osteoporosis development through reducing oxidative stress

Probucol (PBC) is a potent cholesterol-lowering drug and has been studied extensively for its powerful antioxidative stress. The purpose of this study is to investigate the role of PBC in ovariectomized rat model and to explore the mechanism of osteogenic differentiation of MC3TE-E1 Cells. RT-qPCR a...

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Detalles Bibliográficos
Autores principales: Tao, Zhou-Shan, Li, Tian-Lin, Wei, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238135/
https://www.ncbi.nlm.nih.gov/pubmed/35764958
http://dx.doi.org/10.1186/s10020-022-00503-7