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All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice

BACKGROUND: The H9N2 virus can infect not only birds but also humans. The pathogenicity of H9N2 virus infection is determined by an excessive immune response in the lung. All-trans retinoic acid (ATRA), the active metabolite of vitamin A, plays an important regulatory role and has been widely used i...

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Detalles Bibliográficos
Autores principales: Niu, Xiaofei, Wang, Hongyan, Zhao, Lihong, Lian, Pengjing, Bai, Yu, Li, Jingyun, Qiao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238145/
https://www.ncbi.nlm.nih.gov/pubmed/35764970
http://dx.doi.org/10.1186/s12985-022-01809-y