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Defective HIV-1 genomes and their potential impact on HIV pathogenesis

Defective HIV-1 proviruses represent a population of viral genomes that are selected for by immune pressures, and clonally expanded to dominate the persistent HIV-1 proviral genome landscape. There are examples of RNA and protein expression from these compromised genomes which are generated by a var...

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Detalles Bibliográficos
Autores principales: Kuniholm, Jeffrey, Coote, Carolyn, Henderson, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238239/
https://www.ncbi.nlm.nih.gov/pubmed/35764966
http://dx.doi.org/10.1186/s12977-022-00601-8