scDART: integrating unmatched scRNA-seq and scATAC-seq data and learning cross-modality relationship simultaneously

It is a challenging task to integrate scRNA-seq and scATAC-seq data obtained from different batches. Existing methods tend to use a pre-defined gene activity matrix to convert the scATAC-seq data into scRNA-seq data. The pre-defined gene activity matrix is often of low quality and does not reflect t...

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Detalles Bibliográficos
Autores principales: Zhang, Ziqi, Yang, Chengkai, Zhang, Xiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238247/
https://www.ncbi.nlm.nih.gov/pubmed/35761403
http://dx.doi.org/10.1186/s13059-022-02706-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238247/
https://www.ncbi.nlm.nih.gov/pubmed/35761403
http://dx.doi.org/10.1186/s13059-022-02706-x

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