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Pericellular heparan sulfate proteoglycans: Role in regulating the biosynthetic response of nucleus pulposus cells to osmotic loading

BACKGROUND: Daily physiologic loading causes fluctuations in hydration of the intervertebral disc (IVD); thus, the embedded cells experience cyclic alterations to their osmotic environment. These osmotic fluctuations have been described as a mechanism linking mechanics and biology, and have previous...

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Detalles Bibliográficos
Autores principales: Krull, Carly M., Rife, Jordan, Klamer, Brett, Purmessur, Devina, Walter, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238280/
https://www.ncbi.nlm.nih.gov/pubmed/35783912
http://dx.doi.org/10.1002/jsp2.1209