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Cytokine TGFβ Gene Polymorphism in Asthma: TGF-Related SNP Analysis Enhances the Prediction of Disease Diagnosis (A Case-Control Study With Multivariable Data-Mining Model Development)

INTRODUCTION: TGF-β and its receptors play a crucial role in asthma pathogenesis and bronchial remodeling in the course of the disease. TGF-β1, TGF-β2, and TGF-β3 isoforms are responsible for chronic inflammation, bronchial hyperreactivity, myofibroblast activation, fibrosis, bronchial remodeling, a...

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Detalles Bibliográficos
Autores principales: Panek, Michał, Stawiski, Konrad, Kaszkowiak, Marcin, Kuna, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238410/
https://www.ncbi.nlm.nih.gov/pubmed/35774789
http://dx.doi.org/10.3389/fimmu.2022.746360