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Active RhoA Exerts an Inhibitory Effect on the Homeostasis and Angiogenic Capacity of Human Endothelial Cells

BACKGROUND: The small GTPase RhoA (Ras homolog gene family, member A) regulates a variety of cellular processes, including cell motility, proliferation, survival, and permeability. In addition, there are reports indicating that RhoA‐ROCK (rho associated coiled‐coil containing protein kinase) activat...

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Detalles Bibliográficos
Autores principales: Hauke, Michael, Eckenstaler, Robert, Ripperger, Anne, Ender, Anna, Braun, Heike, Benndorf, Ralf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238636/
https://www.ncbi.nlm.nih.gov/pubmed/35699166
http://dx.doi.org/10.1161/JAHA.121.025119