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Integrating a Polygenic Risk Score for Coronary Artery Disease as a Risk‐Enhancing Factor in the Pooled Cohort Equation: A Cost‐Effectiveness Analysis Study

BACKGROUND: Cardiovascular diseases are the leading cause of death in the United States, yet a significant proportion of adults at high risk remain undetected by standard screening practices. Polygenic risk score for coronary artery disease (CAD‐PRS) improves precision in determining the 10‐year ris...

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Detalles Bibliográficos
Autores principales: Mujwara, Deo, Henno, Geoffrey, Vernon, Stephen T., Peng, Siyang, Di Domenico, Paolo, Schroeder, Brock, Busby, George B., Figtree, Gemma A, Bottà, Giordano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238642/
https://www.ncbi.nlm.nih.gov/pubmed/35699184
http://dx.doi.org/10.1161/JAHA.121.025236