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Genetic Architecture of Plasma Alpha‐Aminoadipic Acid Reveals a Relationship With High‐Density Lipoprotein Cholesterol

BACKGROUND: Elevated plasma levels of alpha‐aminoadipic acid (2‐AAA) have been associated with the development of type 2 diabetes and atherosclerosis. However, the nature of the association remains unknown. METHODS AND RESULTS: We identified genetic determinants of plasma 2‐AAA through meta‐analysis...

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Detalles Bibliográficos
Autores principales: Shi, Mingjian, Wang, Chuan, Mei, Hao, Temprosa, Marinella, Florez, Jose C., Tripputi, Mark, Merino, Jordi, Lipworth, Loren, Shu, Xiao‐Ou, Gerszten, Robert E., Wang, Thomas J., Beckman, Joshua A., Gamboa, Jorge L., Mosley, Jonathan D., Ferguson, Jane F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238724/
https://www.ncbi.nlm.nih.gov/pubmed/35621206
http://dx.doi.org/10.1161/JAHA.121.024388