Pyruvate Kinase M2 Protects Heart from Pressure Overload‐Induced Heart Failure by Phosphorylating RAC1

BACKGROUND: Heart failure, caused by sustained pressure overload, remains a major public health problem. PKM (pyruvate kinase M) acts as a rate‐limiting enzyme of glycolysis. PKM2 (pyruvate kinase M2), an alternative splicing product of PKM, plays complex roles in various biological processes and di...

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Detalles Bibliográficos
Autores principales: Ni, Le, Lin, Bowen, Hu, Lingjie, Zhang, Ruoyu, Fu, Fengmei, Shen, Meiting, Yang, Jian, Shi, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238738/
https://www.ncbi.nlm.nih.gov/pubmed/35656980
http://dx.doi.org/10.1161/JAHA.121.024854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238738/
https://www.ncbi.nlm.nih.gov/pubmed/35656980
http://dx.doi.org/10.1161/JAHA.121.024854

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