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Carrier Proteins Facilitate the Generation of Antipolysaccharide Immunity via Multiple Mechanisms

Capsular polysaccharides (CPSs) are important antigenic targets against bacterial infections. As T-independent antigens, however, CPSs elicit short-lived immune responses in adults and are poorly immunogenic in young children. Coupling CPS with protein carriers enhances anti-CPS responses and genera...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Thompson, Claudette, Ma, Nicole, Lu, Ying-Jie, Malley, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239039/
https://www.ncbi.nlm.nih.gov/pubmed/35420488
http://dx.doi.org/10.1128/mbio.03790-21