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Carrier Proteins Facilitate the Generation of Antipolysaccharide Immunity via Multiple Mechanisms
Capsular polysaccharides (CPSs) are important antigenic targets against bacterial infections. As T-independent antigens, however, CPSs elicit short-lived immune responses in adults and are poorly immunogenic in young children. Coupling CPS with protein carriers enhances anti-CPS responses and genera...
Autores principales: | Zhang, Fan, Thompson, Claudette, Ma, Nicole, Lu, Ying-Jie, Malley, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239039/ https://www.ncbi.nlm.nih.gov/pubmed/35420488 http://dx.doi.org/10.1128/mbio.03790-21 |
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