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Autophagy Underlies the Proteostasis Mechanisms of Artemisinin Resistance in P. falciparum Malaria
Emerging resistance to artemisinin (ART) has become a challenge for reducing worldwide malaria mortality and morbidity. The C580Y mutation in Plasmodium falciparum Kelch13 has been identified as the major determinant for ART resistance in the background of other mutations, which include the T38I mut...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239046/ https://www.ncbi.nlm.nih.gov/pubmed/35420484 http://dx.doi.org/10.1128/mbio.00630-22 |