Structure of a Vaccine-Induced, Germline-Encoded Human Antibody Defines a Neutralizing Epitope on the SARS-CoV-2 Spike N-Terminal Domain

Structural characterization of infection- and vaccination-elicited antibodies in complex with antigen provides insight into the evolutionary arms race between the host and the pathogen and informs rational vaccine immunogen design. We isolated a germ line-encoded monoclonal antibody (mAb) from plasm...

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Detalles Bibliográficos
Autores principales: Altomare, Clara G., Adelsberg, Daniel C., Carreno, Juan Manuel, Sapse, Iden A., Amanat, Fatima, Ellebedy, Ali H., Simon, Viviana, Krammer, Florian, Bajic, Goran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239078/
https://www.ncbi.nlm.nih.gov/pubmed/35467422
http://dx.doi.org/10.1128/mbio.03580-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239078/
https://www.ncbi.nlm.nih.gov/pubmed/35467422
http://dx.doi.org/10.1128/mbio.03580-21

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