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The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication

Chikungunya virus (CHIKV) is an arthritogenic reemerging virus replicating in plasma membrane-derived compartments termed “spherules.” Here, we identify the human transmembrane protein CD81 as host factor required for CHIKV replication. Ablation of CD81 results in decreased CHIKV permissiveness, whi...

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Detalles Bibliográficos
Autores principales: Lasswitz, Lisa, Zapatero-Belinchón, Francisco J., Moeller, Rebecca, Hülskötter, Kirsten, Laurent, Timothée, Carlson, Lars-Anders, Goffinet, Christine, Simmons, Graham, Baumgärtner, Wolfgang, Gerold, Gisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239085/
https://www.ncbi.nlm.nih.gov/pubmed/35612284
http://dx.doi.org/10.1128/mbio.00731-22