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Paneth Cells Protect against Acute Pancreatitis via Modulating Gut Microbiota Dysbiosis

Acute pancreatitis (AP) is usually accompanied by intestinal failure, but its mechanism is still unclear. In AP patients, the functions of Paneth cells (lysozyme, HD5, Reg3γ, and Wnt3a) decreased. Compared with AP mice, injuries and inflammation of the pancreas and ileum were aggravated in AP mice t...

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Detalles Bibliográficos
Autores principales: Fu, Yang, Mei, Qixiang, Yin, Nuoming, Huang, Zehua, Li, Baiwen, Luo, Shengzheng, Xu, Binqiang, Fan, Junjie, Huang, Chunlan, Zeng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239092/
https://www.ncbi.nlm.nih.gov/pubmed/35491818
http://dx.doi.org/10.1128/msystems.01507-21