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Peptidoglycan Recycling Promotes Outer Membrane Integrity and Carbapenem Tolerance in Acinetobacter baumannii

β-Lactam antibiotics exploit the essentiality of the bacterial cell envelope by perturbing the peptidoglycan layer, typically resulting in rapid lysis and death. Many Gram-negative bacteria do not lyse but instead exhibit “tolerance,” the ability to sustain viability in the presence of bactericidal...

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Detalles Bibliográficos
Autores principales: Islam, Nowrosh, Kazi, Misha I., Kang, Katie N., Biboy, Jacob, Gray, Joe, Ahmed, Feroz, Schargel, Richard D., Boutte, Cara C., Dörr, Tobias, Vollmer, Waldemar, Boll, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239154/
https://www.ncbi.nlm.nih.gov/pubmed/35638738
http://dx.doi.org/10.1128/mbio.01001-22