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Potency of Fusion-Inhibitory Lipopeptides against SARS-CoV-2 Variants of Concern

The ability of SARS-CoV-2 to evolve in response to selective pressures poses a challenge to vaccine and antiviral efficacy. The S1 subunit of the spike (S) protein contains the receptor-binding domain and is therefore under selective pressure to evade neutralizing antibodies elicited by vaccination...

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Detalles Bibliográficos
Autores principales: Schmitz, Katharina S., Geers, Daryl, de Vries, Rory D., Bovier, T. Francesca, Mykytyn, Anna Z., Geurts van Kessel, Corine H., Haagmans, Bart L., Porotto, Matteo, de Swart, Rik L., Moscona, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239157/
https://www.ncbi.nlm.nih.gov/pubmed/35695453
http://dx.doi.org/10.1128/mbio.01249-22